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What does it mean to have elevated MCH and MCHC levels?

Answer:

mchc results aren't usually reported, it is mainly used as a guideline for analyser function, if MCHC is elevated it us a good indicator the analyser is in need of attention, i.e if it is averaging high. However if the result is true it is a good indicator of Cold agglutination taking place in the sample, if the mchc corrects after the sample has been warmed for >15minutes @37C this is clinically reportable, if the mchc does not correct and is only slightly elevated e.g 367 372 it can be a rare true case of hereditary spherocytosis.

An elevated MCHC blood level on laboratory findings can also indicate a Vitamin B12 or folic acid deficiency.

A high MCH level in the blood can be due to a macrocytic anemia. This is typically an anemia caused by the inability of hemoglobin cells to divide properly before they get too big and are then inefficient at carrying the appropriate nutrients to the body. A Vitamin B12 deficiency, poisons, chemotherapy, alcoholism, and other chemicals that damage DNA which in turn doesn't make the blood components develop properly or split in time is also a factor in macrocytic anemia. In all these cases, the MCH will be elevated and an indicator of the physical disorder.

First answer by ID3398480322. Last edit by D4est. Contributor trust: 1252 [recommend contributor ]. Question popularity: 2 [recommend question].

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