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Sporozoites are injected into the blood stream of a person by the femal anopheles mosquito. They go straight to the hepatocytes, to form a cystic structure known as a schizont. In 1 - 2 weeks this ruptures releasing hundreds of infective meroizoites in the blood. These merozoites are highly immunogenic, causing the circulating neutrophils and macrophages of the reticulo-endothelial system to release large number of cytokines, and other inflammatory mediators. In particular IL-6 and TNF. These cause the fever with chills and shivering. Some of the merozoites are sequestered by the reticulo-endothelial system. The majority left over infect other red blood cells. Inside the cells they divide, rupture the cell and release another 20 or so merozoites per organism. In this process large number of red blood cells are destroyed resulting in anemia, and hemoglobin in the blood and urine. The red blood cells also become fragile, are destroyed by the spleen, and there is hypersplenism (enlarged spleen). Fragile, infected red blood cells can also lodge in vessels causing damage to that particular organ. This is of major significance in the brain where cerebral malaria can result

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12y ago
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9y ago

Malaria is a serious, infectious disease spread by certain mosquitoes. It is most common in tropical climates. It is characterized by recurrent symptoms ofchills, fever, and an enlarged spleen. The disease can be treated with medication, but it often recurs. Malaria is endemic (occurs frequently in a particular locality) in many third world countries. Isolated, small outbreaks sometimes occur within the boundaries of the United States.

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The symptoms of malaria:

  • Shivering or shaking or cold spells
  • Fever or hot spells, sweating
  • Severe headaches, may be accompanied by nausea
  • Muscle pains
  • Excessive tiredness

The impact of malaria on the human body:

  • Anaemia due to the destruction of red blood cells
  • Reduced resistance to other diseases
  • Disturbance to liver function
  • If pregnant, may result in miscarriage

the malaria parasite destroys red AND white blood cells which can lead to damage of the spleen, kidneys, liver and brain.

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9y ago

Body tries to kill the malaria parasite by high grade fever. By the way the syphilis causing bacteria is killed by this high temperature. Body forms the humeral antibodies against the malaria parasites. There is enlargement of liver and spleen. Spleen can enlarge enormously.

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13y ago

Some symptoms of malaria include high fever, headache, vomiting, diarrhea, nausea, profuse sweating as body temperature falls and moderate to severe shaking chills.

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13y ago

Malaria is a life threatening disease. It causes headaches, vomiting, nausea, the chills, and shaking.

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12y ago

Critically high fevers, sweats , and chills. Patient in and out of consciousness. Left untreated, death.

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11y ago

it kills you

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Q: What does malaria do to humans?
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Related questions

What primate can get malaria?

Humans for one...


Which creature was commonly associated with malaria?

Malaria is a mosquito-borne infectious disease of humans


Does a parasite give humans chickenpox or malaria?

Chickenpox is caused by a virus, and malaria is caused by a parasite.


What is malarai?

Malaria is a infectious disease of humans caused by eukaryotic protists of the genus Plasmodium.see more about malaria CDC information at: cdc.gov/malaria/


What is malaria caused by that is transferred to humans by the bite of an infected mosquito?

the female mosquito transfer malaria by its saliva into blood of human , which causes break down of RBCs


How Is Malaria Passed On To Humans?

typically via mosquitoes


Is transferred to humans by the bite of an infected mosquito?

malaria


Which mosquito is the root cause for spread of malaria?

Malaria is transmitted among humans by female mosquitoes of the genus Anopheles.


Who does malaria affect?

Humans bitten by female anopheles mosquitoes


Can pets catch malaria?

Yes. But not exactly in the way humans do.


How can mosquitoes effect humans?

West Nile Virus.. Malaria..


What do mosquitoes do to humans?

Give them mosquito bites, and sometimes malaria