Schisandra fruit contains at least 30 different lignans. Lignans, which are sometimes described as phytoestrogens (plant-derived compounds with estrogen-like activity), are known to have liver-protective (anti-hepatotoxic) action
Historically, it was used to treat mental illness, night sweats, coughs, thirst, insomnia , chronic dysentery (diarrhea containing blood and mucus), premature ejaculation, and physical exhaustion.
Schisandra is safe for long-term use; it has relatively few side effects. It has, however, been reported to cause upset stomach, heartburn , decreased appetite, and skin rash.