What effects do cystic fibrosis have on infants?

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What is Cystic Fibrosis?

Cystic fibrosis is a genetic disorder which affects the lungs and pancreas. It causes the lungs to get clogged with mucus, which in turn makes the lungs a breeding ground for bacteria. In the pancreas, it blocks the pancreas from absorbing enzymes, which makes its victims prone to malnutrition. Often times, they have to take treatments such as lung therapy every day, as well as enzyme supplements on a daily basis. The average life expectancy is 37. . Cystic Fibrosis is caused by a defective gene which causes a thick, sticky mucus. It builds up in the lungs and pancreas (the organ that helps to break-down food.) Cystic Fibrosis results in life-threatening lung infections and digestive problems. Symptoms are varied, but the most common are: No bowel movements in first 24 - 48 hours of life (baby!) Stools that are pale or clay colored, foul smelling or float. Infants can have salty tasting skin. Recurrent respiratory infections, such as pneumonia or sinusitis. Coughing/wheezing. Weight loss or can't gain weight normally in childhood. Diarrhea, delayed growth and fatigue. . Cystic Fibrosis is the most common fatal genetic disease occurring in about 1 in 30,000 births. The gene must be inherited from both the mother and the father. Children inheriting only one copy of the gene are carriers but do not display symptoms. Average life expectancy for Cystic Fibrosis is approximately 32 years of age. There are many treatments but no cure. People with Cystic Fibrosis are at high risk of developing other conditions such as Cystic Fibrosis related Arthritis and Cystic Fibrosis related Diabetes, Liver failure and ultimately respiratory failure leading to death. Once a person with Cystic Fibrosis loses enough lung function the only other treatment is a lung transplant

Who is most likely to get cystic fibrosis?

About one of every 30 white people (about 3 in 100 or about 3%) carries the gene. If a relative of yours has CF, or is known to be a carrier of CF, your chance of being a carrier is greater based on your family history than your ethnic background. Cystic fibrosis is one of the most common life-shortening, childhood-onset inherited diseases. In the United States, 1 in 3900 children are born with CF. It is most common among Europeans and Ashkenazi Jews; one in twenty-two people of European descent are carriers of one gene for CF, making it the most common genetic disease in these populations. Ireland has the highest rate of CF carriers in the world (1 in 19).

Is cystic fibrosis common in the US?

Yes. Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that: * clogs the lungs and leads to life-threatening lung infections; and * obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food.

How does Cystic Fibrosis effect the human body?

It effects the body in a number of ways: (1) Lungs - It is common for people with CF to encounter some difficulties with their lungs. But a combination of physiotherapy and medication can help control lung infections and prevent lung damage. To avoid the risk of cross infection, it is recommended that people with CF do not come into close contact with others with Cystic Fibrosis, which is why in so many hospitals people with CF are segregated. (2) Digestive System - mucus blocks the digestive system making it hard for people with cystic fibrosis to digest food. This can be helped with the medicine "Creon" which is an enzyme which helps to break food down. (3) Meconium ileus - In every ten babies born with CF, one is ill in the first few days of life with a bowel obstruction known as Meconium Ileus. (4) Bones - due to the nutritional and other problems involved with the disease (5) Infertility - Although people with CF are not deemed as 100% infertile, most men with Cf are due to blockages in the tubes that carry sperm, which causes infertility. Because underweight women are more likely to have irregular menstrual cycles, the nutritional problems associated with CF may affect fertility. (6) Liver- Cystic Fibrosis can cause the blockage of small ducts in the liver. This only happens to approximately 8% of people who have CF, but it is a serious health risk and may necessitate a liver transplant

What is the history of cystic fibrosis?

Cystic fibrosis has had reported incidents since the early 17th century. The poem Woe Is the Child gives a description of a child at this time period who had CF. The first clear description and medical entry for CF was made in 1938. Cystic fibrosis has had reported incidents since the early 17th century. The poem Woe Is the Child gives a description of a child at this time period who had CF. The first clear description and medical entry for CF was made in 1938.

What celebrities have cystic fibrosis?

I'm not aware of any celebrities with CF but Celine Dion used to be the celebrity patron for the Canadian CF Foundation as her niece passed away from CF.

Is Cystic Fibrosis deadly?

It can be very deadly. For the source and more detailed information concerning your request, click on the related links section (Wikipedia) indicated directly below this answer section.

If you have Cystic Fibrosis can you get your partner pregnant?

According to my earlier research on the subject (source forgotten, sorry):\n. \nMore than 95% of male cystic fibrosis sufferers are sterile.\n. \nIt's possible but highly unlikely unless you're using some form of artificial insemination or you happen to be in the 5% of non-sterile male cystic fibrosis sufferers.

What are the effects of cystic fibrosis?

CF causes secretion of abnormally viscous mucus that clogs the respiratory that predisposes the child to respiratory infections. It appears that infection of CF victims' lungs with the bacterium Pseudomonas aeruginosa trips a genetic swithc that causes the disabled cells to churn out oceans of abnormal muchin ( the primary component of mucus). The bacteria then feed on the stagnant pools of mucus and keep sending signals to the cells to make more. Toxins released by the bacteria and the local inflammatory reaction set up by the immune response both damage the lungs. Unable to reach the bacteria embedded in the mucus, the immune cells begain to attack the lung tissue, turning the air sacs into bloated cysts. This can be found in the 8th edition of Human Anatomy & Physiology, page 843

Effects of cystic fibrosis on digestion?

The thick mucus seen in the lungs and its counterpart in thickened secretions from the pancreas, an organ responsible for providing digestive juices which help break down food. These secretions block the movement of the digestive enzymes into the duodenum and result in irreversible damage to the pancreas, often with painful inflammation (pancreatitis). The lack of digestive enzymes leads to difficulty absorbing nutrients with their subsequent excretion in the faeces, a disorder known as malabsorption. Malabsorption leads to malnutrition and poor growth and development because of calorie loss. Individuals with CF also have difficulties absorbing the fat-soluble vitamins A, D, E, and K. In addition to the pancreas problems, people with cystic fibrosis experience more heartburn, intestinal blockage by intussusception, and constipation. Older individuals with CF may also develop distal intestinal obstruction syndrome when thickened faeces cause intestinal blockage.

To be a cystic fibrosis carrier do your parents have to have a cystics fibrosis gene?

Yes, since the disease is a recessive inherted trait BOTHparents must carry the gene but will not have the disease itself.Approximately 30,000 people in the United States have cysticfibrosis. . An additional ten million more-or about one in every 31Americans-are carriers of the defective CF gene, but do not havethe disease. The disease is most common in Caucasians, but it canaffect all races.

How does cystic fibrosis effect the cell membrane?

Cystic fibrosis is caused by defective CFTR protein. CFTR is an ion channel that transports chloride ions across epithelial cell membranes.

If you are a carrier for Cystic Fibrosis is it possible you have cystic fibrosis?

No. You can be a carrier of the CF gene and be healthy. If you have Cystic Fibrosis it would more than likely show in early childhood. Both your parents would have to be a carrier of the gene for you to be born with Cystic Fibrosis. When two carriers of the CF gene parent a child together there is a 1 in 4 chance of the child being born with Cystic Fibrosis. . no because you don't have the other gene.

What does cystic fibrosis?

it is a infection in the liver an dlungs and can kill u...... if u have exercise everyday and drink lots of fluids an have a healthy diet also u can take medicines to help treat this dissorder Edit from another person: Cystic Fibrosis is not an infection, it is an inherited genetic disorder. Nor is it restricted to the liver and lungs, as my mother has it in her uterus and ovaries. However, I believe the (incomplete) question was about what it does . Basically, it causes tissues to become hard tumors, which can continue to grow in size significantly.

Does Cystic Fibrosis effect Reproduction?

Yes it can, the thick and viscous mucus can block the sperm ducts for example and can therefore lead to sterility, as the sperm cannot be released.

How does cystic fibrosis effect someones life?

The thick mucus fills the lungs, making it hard for the effected person to breath. It also can effect the digestion of the person and often leads to an early death. The effected person has to attend regular physiotherapy sessions to stop them suffocating

What are 3 emotional effects of cystic fibrosis?

In my experience with my long-term boyfriend (32 yo. CF patient), the biggest emotional effect I see with him having CF has been that since the time he was very little, he remembers feel different. As an adult this has turned into feelings of loneliness and being alone. It has had many serious implications on our relationship and other relationships he has had.

How can you get cystic fibrosis?

Cystic fibrosis is a genetic disease and can only be inherited through genes. It all depends on your parents alleles. Let's say that the allele for cystic fibrosis is c. If your Mum has the allele Cc it means she is hetrozygous. If you Dad has the same allele he is also hetrozygous. When they had children, the two small c's could come together to make a child with the alleles cc. (This means that the child has cystic fibrosis and has homozygous reccessive alleles.) When they had children their alleles could also come together to make CC (homozygous dominant- this means that person doesn't carry an allele for cystic firbrosis and will never get it. This means that if that person had children with another person who has the alleles CC, their child wouldn't get it), or it could make a child with Cc alleles. The child with Cc alleles wouldn't get cystic fibrosis because the allele big C (dominant allele) over powers the allele small c (reccessive- the cystic fibrosis allele). Although this person doesn't have cystic fibrosis their children might because they carry the allele for cystic fibrosis, which is c.

What chromosome does cystic fibrosis effect?

The gene on chromosome 7 produces a protein called cystic fibrosis trans-membrane regulator. Mutation in the DNA level of chromosome 7 leads to the absence of this protein which leads to cystic fibrosis. Cystic fibrosis is a recessive disease.

What is it like to have cystic fibrosis for a day?

Its absolutely horrible. Your day is full of medicine and coughing. So yeah, it pretty much sucks.

Meds you use for cystic fibrosis?

There are an infinite number of medicines that CF patients may use, but only five are available exclusively for CF patients. Tobramycin, an antibiotic, comes in two forms, known and Tobi and Tobra. Tobi is inhaled through a nebulizer, while Tobra is given intravenously through a PICCline, peripheral IV, or port. Colistimethate is also an antibiotic given either inhaled or intravenously, and is called Colistin in both cases. Hypertonic saline is just what you think it is: saltwater. Often used in the 7% concentration, it is inhaled and the salt dries out the lung cells, forcing the body to concentrate more water to the lungs. In turn, the cells take in water to neutralize the effect of the salt, and the cilia in the lungs are able to move again. Pulmozyme is a geneticly enhanced drug that breaks down the DNA which makes mucus in the lungs so thick, so it is easier to cough up. Finally, aztreonam, better known as Cayston, just passed FDA approval last year, and is another inhaled antibiotic.

Can you get cystic fibrosis from your mother?

Depends. If your mother has cystic fibrosis and your father is a carrier, there is a 50% chance that any of their children will have cystic fibrosis. If the father is not a carrier, no children will have cystic fibrosis, but they will all be carriers.

How do you find out you have Cystic Fibrosis?

you have to talk to your doctor. most commonly you take what is called a "sweat test" if levels come back abnormally higher, chances are you have CF (cystic Fibrosis)

How is Cystic fibrosis inherted?

All through the genes and alleles. Cystic fibrosis is a genetic disease and can only be inherited through genes. It all depends on your parents alleles. Let's say that the allele for cystic fibrosis is c. If your Mum has the allele Cc it means she is hetrozygous. If you Dad has the same allele he is also hetrozygous. When they had children, the two small c's could come together to make a child with the alleles cc. (This means that the child has cystic fibrosis and has homozygous reccessive alleles.) When they had children their alleles could also come together to make CC (homozygous dominant- this means that person doesn't carry an allele for cystic firbrosis and will never get it. This means that if that person had children with another person who has the alleles CC, their child wouldn't get it), or it could make a child with Cc alleles. The child with Cc alleles wouldn't get cystic fibrosis because the allele big C (dominant allele) over powers the allele small c (reccessive- the cystic fibrosis allele). Although this person doesn't have cystic fibrosis their children might because they carry the allele for cystic fibrosis, which is c.

How can a child with cystic fibrosis have two parents that do not have cystic fibrosis?

a child with cf has parents which 'carry' the cf gene therefore they do not have it

How you inherit cystic Fibrosis by the parents?

Cystic fibrosis is an autosomal recessive disease. That means that each parent has to carry a mutation and will have a 1 in 4 (25%) chance of having a child with CF. The previous answer is not correct. __________________________________________________________________ You inherit cystic fibrosis from either one parent or both. It is to do with genetic mapping. Cystic fibrosis is a recessive gene and can be carried by our parents even if they do not suffer from it, it's like in a carrier(someone who does not suffer from CF but still has the gene) the cystic fibrosis gene is 'hiding'. When we crete gametes (sperm and eggs) the genes have to split. For example your father could have the gene Ff and they would split and become F f. The capital F is the dominant gene and the small f is the recessive gene, in this case cystic fibrosis. When an egg is fertilised the separate gene from both parents join together. If a man and women have one child, and both parents had the recessive gene of CF then the likelihood of their first child having cystic fibrosis is high, 50% in fact. Here is a diagram which might help explain Parents Mother + Father Genotype (genes) Ff Ff Gametes(sperm+egg) F f F f Offspring FF ff 50% 50% I hope this helped a little. I didn't go into full detail becasue there is a lot more to it then what i have said and it is a lot more comlicated. If you can, try to go on a revision site which may help.

Cystic fibrosis is it monosomy 21?

No. Cystic fibrosis is an autosomal recessive disease caused by mutations found on chromosome 7.

Is cystic fibrosis a rare disease?

Cystic fibrosis is considered a rare disease. There are about 30,000 people in the United States and 70,000 people worldwide with CF. According to the National Institutes of Health (NIH) a disease is considered rare if it affects fewer than 200,000 people in the United States.

Is cystic fibrosis painful?

Cystic fibrosis has no cure. However, treatments have greatlyimproved in recent years. Early treatment for cystic fibrosis canimprove both quality of life and lifespan.

Can people with cystic fibrosis have kids?

Yes people with cystic fibrosis can have children however they may need the help of a fertility specialist. Nearly all men with CF have congenital bilateral absence of the vas deferens (CBAVD) which means that they are missing the tubes that carry the sperm from the testes to the ejaculatory duct. Many women with CF may have difficulty getting pregnant due to extremely thick cervical mucus.

How is a child born with cystic fibrosis?

they inherit CF when both parents genetically have the faulty gene. there is a 25% chance of their child having it when both have the gene. hope this helps

Are there any fundraisers for cystic fibrosis?

Here are a couple for you to review: This one is a national walk called Great Strides . You can find a walker to sponsor, or become a walker yourself and get sponsors to help you on your walk. http://www.cff.org/great_strides/ . Clicks! for Cystic Fibrosis has created an easy way for individuals to ensure their favorite charity receives a portion of the profit from their online purchases. When an internet user wishes to make a purchase with any of over 400 leading online retailers (such as Barnes and Noble, Wal-Mart, Disney, Macy's, Dell, Linens N Things, Staples, and many, many more), all they need to do is locate them within the Clicks! for Cystic Fibrosis retailer directory and use the link provided for that vendor. http://www.squidoo.com/cysticfibrosis . Search your local area as well. Many businesses will help people start a fund raiser for good causes, as it gives them a positive and free way to be looked at by the community. Also placing adverts in your local newspaper or even craigslist could draw attention from other people who are looking to do the same thing or may share the same interests in that cause.

Does Cystic Fibrosis affect kids?

yes, everyone who has cystic fibrosis has had it from birth therefore they have it when they are children.

How do parents who do not have cystic fibrosis produce a child who has cystic fibrosis?

"Cystic fibrosis (CF) is an autosomal recessive disease. That means that if both parents have cystic fibrosis, so will any children that they have. If one parent has cystic fibrosis and the other does not, then the chance drops dramatically (almost to zero)." Not wholly correct. CF is a recessive disease which means that you must posses two copies of the faulty gene (1 from your mother and 1 from your father) in order to present with the condition. If one parent has CF then the chances of them presenting with the disease are as follows. If the other parent also has CF, then 100% as you stated If the other parent is a carrier (has one Normal gene and one faulty gene) then there is a 50% (not almost 0%) chance that the child will have CF, and if not, they will be a carrier. If the other parent doesn't have CF and doesn't carry the faulty gene. Then the child will not have CF but will be a carrier. The original question was how can two parents who do not have CF produce a child that has CF. In this instance, both parents have to carry the recessive gene, but it doesn't present in them because the gene is recessive, it is overruled by the dominant, normal gene. Using a genetic cross diagram known as punnett square, we can work out that there will be a 25% chance of the child between the two parents who carry the faulty gene, inheriting CF, a 50% chance they will be a carrier, and a further 25% chance that they will neither have the disease or be a carrier. Furthermore, CF also effects the reproductive system (predominantly in males i believe), so many sufferers are unable to have children.

What is the underlying defect in cystic fibrosis?

The underlying defect in cystic fibrosis is an improperly folded CFTR (cystic fibrosis transmembrane conductance regulator) protein. Depending on the type of mutation, the misfolded CFTR protein either doesn't reach the cell membrane or reaches the cell membrane but doesn't function properly. CFTR is responsible for regulating transport of chloride and sodium ions into and out of cells. The movement of these ions is crucial in helping to control the movement of water in tissues which is what helps thin mucus. Without properly functioning CFTR the mucus becomes thick and sticky. This viscous mucus builds up in and clogs organs.

How do you know you got cystic fibrosis?

Most babies with cystic fibrosis are diagnosed at birth from meconium ileus (stomach blockage) however if undetected at birth if a doctor is suspicious he can give the "sweat test" which measures the concentration of chloride that is excreted in sweat. for a further list of symptoms here's the cystic fibrosis website in the below related link.

Can you prevent cystic fibrosis?

The only way to prevent CF is to get both parents tested before conceiving then making the difficult decision to go ahead and conceive (if both tested as a carrier of the CF gene). If both parents are carriers its a 25% chance of the child having CF.

Is cystic fibrosis spreadable?

Good Question. The answer is cystic fibrosis is not contagious, however, people with cystic fibrosis tend to carry bacterial infections that can cause serious issues to other people with CF, so infection control procedures should be used when two or more cystics are around each other. General population folks need not fear of getting cystic fibrosis from others - it's a hereditary disease.

How does cystic fibrosis affect the person?

Cystic fibrosis can affect individuals in numerous ways. It can cause breathing difficulties, this is because the thick mucus blocks the airways reducing the efficiancy of gas exchange. The mucus can also block the pancreatic ducts, meaning that the pancreatic enzymes can't move into the duodenum and digest food, this produces fibrous cysts. Thirdly the mucus may block sperm ducts and cause infertility. Also, the thick and sticky mucus may trap pathogens, these pathogens may pentrate the epithelial cells and cause infections.

Is cystic fibrosis geneitc?

Yes it is a genetic disorder. For a baby to be born with Cystic Fibrosis, both parents must be carriers of the faulty CF gene. Where both parents carry the faulty gene, each child has a one in four chance of having CF, a two in four chance of being a carrier and a one in four chance of not having any CF genes.

How do black people get cystic fibrosis?

The Same Way Any other person would get CF (Cystic Fibrosis), although it's Very Rare For African Americans to get it. Cystic Fibrosis is most common among Caucasians.

How is the disorder for cystic fibrosis inherited?

For a baby to be born with Cystic Fibrosis, both parents must be carriers of the faulty CF gene. Where both parents carry the faulty gene, each child has a one in four chance of having CF, a two in four chance of being a carrier and a one in four chance of not having any CF genes.

Can cystic fibrosis patients date?

Yes absolutely. They live pretty normal lives like anyone else but the life can be shorter.

Which gene causes cystic fibrosis?

Cystic Fibrosis is caused by the gene which codes for the protein CFTR--Cystic Fibrosis Transmembrane Conductance Regulator, which is found on chromosome 7. The protein transports chloride ions across epithelial cell membranes.

What happens to the body with cystic fibrosis?

Cystic fibrosis affects the body's ability to move salt and water in and out of cells. This defect causes the lungs and pancreas to secrete thick mucus, blocking passageways and preventing proper function.

How do you manage cystic fibrosis?

receive physiotherapy, which is a system of massages to remove as much excess mucus as possible.

Do environmental factors effect cystic fibrosis?

Yes, as cystic fibrosis creates a thicker mucus that keeps in bacteria, having a polluted or non-hygienic environment can easily worsen the chronic infections one is prone to get.

What are the social effects of cystic fibrosis?

CF causes secretion of abnormally viscous mucus that clogs the respiratory that predisposes the child to respiratory infections. It appears that infection of CF victims' lungs with the bacterium Pseud

How can cystic fibrosis effect the child and family?

well it is normally black children who get it because of insufficient nutrition. It weakens the bones and joints in the limbs of the children so that they have random but frequent pain spasms that effect walking and movement all together. The families can be supported by specialists but there is no cure for the disease and it shouldn't get better or worse.

What is the effect of thick mucous in the lungs of children with cystic fibrosis?

Breathing becomes very painful and lung transplants may be needed. Lungs become infected and digestion is also effected which can cause malnutrition. In most cases, children with the condition live quite normally but it eventually worsens until becoming life-threatening. A slew of other complications also occur which are the usual causes of death later in life.