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No, GM vehicle are not equipped with an inertia switch.
The 2011 Cadillac Escalade runs on flex-fuel (FFV).
The 2010 Cadillac Escalade runs on flex-fuel (FFV).
The 2014 Cadillac Escalade runs on flex-fuel (FFV).
The 2013 Cadillac Escalade runs on flex-fuel (FFV).
The 2015 Cadillac Escalade runs on flex-fuel (unleaded/E85).
The 2009 Cadillac Escalade runs on flex-fuel (unleaded/E85).
No there is not you have to drop the tank.
The 2014 Cadillac Escalade-ESV runs on flex-fuel (FFV).
The 2011 Cadillac Escalade-EXT runs on flex-fuel (FFV).
The 2011 Cadillac Escalade-ESV runs on flex-fuel (FFV).
The 2013 Cadillac Escalade-EXT runs on flex-fuel (FFV).