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We have to consider that the temperature is one of the most critical conditions that rule the enzyme activity. Enzymes are proteins that solely work when they are in their proper three-dimensional conformation or shape depending on their tertiary and quaternary conformations based on the interactions of hydrogen bonds and other atomic interactions between atoms within the enzyme molecule. However, this shape is not static but is constantly expanding and contracting. This flexibility is essential to how enzymes bind to other molecules and cause chemical reactions to happen on those molecules. Lowering the temperature slows the motion of molecules and atoms, meaning this flexibility is reduced or even lost. Each enzyme has its zone of comfort (i.e., its metabolic temperature), or optimal temperature range, within which it works best. The lower the temperature the less enzyme activity and over a period of time, enzymes will be deactivated at even moderate temperatures. Storage of enzymes at 5°C or below is generally the most suitable. Some enzymes lose their activity when frozen.

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6y ago
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13y ago

At low temperatures, the enzyme has very little energy to move and thus the rate of reaction slows to the point of almost stopping, although it does not entirely stop unless at absolute zero (In theory).
It is not the same as subjecting the enzyme to high temperatures, where the bonds and molecules vibrate so violently they break and the enzyme changes shape irreparably and denatures - as long as the enzyme is warmed up again, it will resume working as before.

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11y ago

below the required conc. of an enzyme decreases its rate of reaction

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Q: What happens at low temperatures in enzyme activity?
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Related questions

What conditions LEAST likely to denature an enzyme?

low temperatures


Enzyme activity can be negatively affected by what environmental factors a. the presence of metal ions b. low salinity c. temperatures above certain tolerable limits d. a pH value between 6 8?

c. Temperatures above certain tolerable limits


If an enzyme is exposed to an unfavorable pH?

Enzymes shows different enzyme activity in different pH value.If the pH is high or low than the optimum pH there is a decrease in the activity of the enzyme.But if the pH is very high or very low it may lead to the deactivation of the enzyme.


How does initial concentration of substrate effect enzyme activity?

At low concentration of substrate , rate of enzyme action is directly proportional to conc. of substrate .


How does low temperatures affect enzymes?

cold temperatures cause enzymes to inactivate, meaning they are no longer useful. at height temperatures enzymes denature, meaning they are also no longer useful. The difference is that at low temperature, when an enzyme inactivates it can always be heated, and used again. Yet after an enzyme is denatured by heat it is destroyed, this is because the heat causes the enzymes to lose its shape, making it imposible for the substrate to react with the enzyme.


The enzyme phosphofructokinase is an important enzyme that plays a significant regulatory role in glycolysis. Which of the following conditions would be expected to result in increased activity of this enzyme?

Low levels of ATP


How do cold temperatures affect enzymes?

the low temperature makes the enzyme become temporaritly inactive, this means that it is so cold for the enzyme that it simply doesen't do anything. hope this helps!


What happens to an enzyme when its put into a hotter or cooler place?

It is now well established that proteins (enzymes) denature at both high and low temperatures. Denaturation, by heat or cold refers to the loss of the 3-dimensional structure of the enzyme, which otherwise it possesses under physiological conditions.When a enzyme experiences this structural instability, it leads to a loss of its functionality, since the 3D structure of a enzyme can be directly co-related with its function.


Some factors that may influence enzyme activity?

A low temperature can slow down enzyme activity and high temperatures can denature an enzyme making it unusable. pH levels also affect enzyme activity. Every cell has an ideal temperature and pH


What tests for Lesch-Nyhan syndrome?

It is diagnosed by measuring the activity of the HPRT enzyme through a blood test. When the activity of the enzyme is very low it is diagnostic of Lesch-Nyhan syndrome. It can also be diagnosed by DNA testing. This is also a blood test.


Enzymes are usually inactivated at what temperature?

The optimal range for the enzymatic activity goes from 25oC to 32oC.


Is temperature a factor that affects enzyme activity?

yes. at low temperature enzymes won't work as effectively, and at high temperature enzymes are denatured.