What hurricane caused the most deaths in US history?

Answer:
Galveston in 1900.
The official casualty estimates for the city of Galveston itself ranged from 6000 to 8000; the numbers for the whole of Galveston Island were much higher, from 10,000 to 12,000.
First answer by ID3326397534. Last edit by RUClimate. Contributor trust: 332 [recommend contributor recommended]. Question popularity: 6 [recommend question].