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No drug eats holes into the brain, but many people say that MDMA (ecstasy) does. The myth comes from the fact that MDMA causes serotonin receptors to burn out prematurely, causing them to become "down-regulated", inhibiting their ability to bind to serotonin. This situation is not permanent, however, and receptors can return to normal with time. This is one of the body's natural processes as it tries to regulate horomone levels. See [1] and [2].
Another issue with MDMA is its capacity to burn out the brain's serotonin axion terminals with repeated use. This is not an effect of ecstasy directly, but rather the aftereffects of its use. Your brain's axion terminals regularly place both serotonin and dopamine into its synapses, and some of the serotonin is "recycled" back into the axion terminals where it its broken down by MAO. When MDMA causes a depletion of your brain's serotonin reserves, it is left with a relative excess of dopamine, which gets recycled instead of the serotonin. MAO breaks down the dopamine into hydrogen peroxide (think bleach) which is damaging to the axion terminals. Normally dopamine is not recycled in this way, it only occurs whenever there is a lack of serotonin. However, there are drugs (e.g. prozac) that can block this recycling process and actually prevent this damage if taken within 6 hours of dosing with MDMA; currently this has only been tested in animals. See [3] and [4].
[1] http://www.dancesafe.org/slideshow/slide18.html
[2] http://en.wikipedia.org/wiki/Downregulation
[3] http://www.dancesafe.org/slideshow/slide19.html
[4] http://www.dancesafe.org/slideshow/slide20.html
Wiki User
∙ 15y ago
Wiki User
∙ 13y agoI'm a former active addict while I was in rehab door heroin an coke and others they did a brain scan to see how much of my brain was functional after this severe abuse and for me it showed a 15% decrease in
My regular brain function before the drugs it eats at your brain some drugs stay in your system for along time. If you are thinking of using drugs don't do it it's not worth the risk of addiction.
Wiki User
∙ 13y agoEcstasy doesn't put holes in your brain
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How can ecstasy harm the brain?
it takes away serotonin and try to refill it and eventually makes holes and u can get brain damage and more likely chance of heart attack or stroke and mass quantities can kill u
What makes your head fill better from ecstasy?
water cuz ecstasy depletes your hydration level and this will cause the body to start regenerating, thus the brain stops hurting
Is there another benefit to the game sudoku besides entertainment?
It makes your brain quicker.
What do extacy pills do?
They tell your brain to release more serotonin (which makes you happy) than usual. Giving the user a sense of 'ecstasy'
Does ecstasy make you twich?
No, it just makes you feel REALLY good but you feel like crap the next day and it kills alot of brain cells
Can ecstasy make you gain weight?
Ecstasy actually will make you lose weight. The methanphetamine in ecstasy makes it highly addictive. Unlike marijuana, ecstasy makes you not want to eat for many hours. So the more you take ecstasy, the less you'll eat.
What makes your body high Ecstasy ecstasy what makes you dance all night ecstasy?
The best to listen to is house, electro, trance, drum and bass, dubstep, techno. Enjoy your roll :)
What kind of drug makes your pupils big and makes you paranoid?
Cocaine, ecstasy
Do ecstasy not make you have kids?
Nope. But it makes you addictive since its a DRUG!
How does ecstasy affect peoples physical health?
it makes your mom have cancer
How are marijuana and ecstasy similar?
there in no way similar ecstasy gives you energy makes u unhungry. weed makes you hungry and lethargic really they arent similar whatsoever don't know where u heard that from.
What actors and actresses appeared in Violent Sorrow Makes a Modern Ecstasy No. 2 - 2009?
The cast of Violent Sorrow Makes a Modern Ecstasy No. 2 - 2009 includes: Agnes Nystad Petter Width Kristiansen
