What is Wilson disease?

Answer:
it is a rare diorder of abnormal copper metabolism and is characterised by:
hepatolenticular degeneration.
copper get deposited in abnormal amounts in liver and lenticular nucleus of brain leading to necrosis of liver and brain.
low level of copper and ceruloplasmin in plasma with increased excretion of copper in urine,
copper deposition in kidneys causes renal damage.
causes:
failure in the synthesis of ceruloplasmin.
excess copper in plasma.
reduced intestinal excretion of copper.
treatment: penicillamine.
First answer by Princesssingam. Last edit by Princesssingam. Contributor trust: 4 [recommend contributor recommended]. Question popularity: 1 [recommend question].