a. The substrate can be altered so it is induced to fit into the enzyme's active site. b. The enzyme changes its shape slightly as it binds to the substrate. c. The enzyme is altered so it is induced to fit many different types of substrate.
d. Several sites on an enzyme can be induced to act on a substrate.
The hypothesis that an enzyme can be induced to change the shape of its active site slightly if the substrate does not fit the active site exacly.
induce fit- the act of being induceal fitting.
According to lock and key model both the enzymes and the substrate possess specific geometrical shapes that fit exactly into one another. WHILE According to the induced fit model enzymes are more flexible structures and their active site is reshaped as substrate interacts with the enzymes.
Scientific theories can be disproved. This is a key part of the scientific method, creating hypothesis that can be disproved if they are incorrect. However, you can never really prove a hypothesis - you can find evidence that either fits or doesn't fit. If it doesn't fit the hypothesis needs to be revised or thrown out. If the evidence supports the hypothesis, there may be something that you are missing which may reject the hypothesis.
Does it fit all the known facts AND can it be tested against reality.
The induced fit model is the theory that instead of enzymes and substrates fitting exactly together, as in the lock and key model, the enzyme changes shape around the substrate to bind with it. Non-competitive inhibition is where the inhibitor does not fit into the active site, but into another site on the enzyme instead, which changes the shape of the active site.
The experiment must be redone and checked for potential errors; does the conclusion of the experiment continuously disprove the hypothesis, the latter must be changed to fit.
These are the modes: 1. Lock and Key hypothesis 2. Induced Fit Hypothesis
bontot
The theory of enzyme-substrate complex was established by Michaelis and Menton in 1913.According to their theory,enzyme combines with substrate to form enzyme-substrate complex.The transient complex has a lower energy of activation than that of substrate alone.This results in the acceleration of the reaction.The enzyme-substrate complex is broken down into enzyme and products of the reaction. E+S -ES - - -ES - - -E+P The different hypotheses of enzyme-substrate complex formation have been postulated.Early theory was postulated by Emil Fischer.According to this theory,the catalytic site of enzyme is preshaped to fit of the substrate.This hypothesis is called "lock and key" or rigid template.The next hypothesis has been proposed by Koshland in the late 1950s.The hypothesis was called "induced fit".Acccording to this theory,a catalytically active configuration of enzyme molecule and that of the active site can be induced only at the moment of attachment of the substate molecule,that is the substrate induces a conformotional change in the enzyme. At the present time,model of "induced fit" is modified.Binding the substrate with the enzyme leads not only to the conformational change of the protein molecule,but also to a geometrical and electrontopographic rearrangement of the substrate molecules. The modern "induced fit" hypothesis presumes the existence between the enzyme and the substrate of not only spatial or geometrical complementarity,but also electrostatic charge complementarity.
So you know whether it is valid or not. If it isn't modify your hypothesis to fit the results of your experiments.
At what temperature does condensation nuclei form in relation to the ambient temperature as induced by the addition of cold particulates (ice),
They all fit together like a puzzle.
An induced fit is a change in the shape of an enzyme which allows it to react effectively with a substrate. The reason for the alteration is to speed up a chemical reaction.
When substrates change the shape of the active sites in enzymes in order to activate them
tidal hypothesis
According to lock and key model both the enzymes and the substrate possess specific geometrical shapes that fit exactly into one another. WHILE According to the induced fit model enzymes are more flexible structures and their active site is reshaped as substrate interacts with the enzymes.
induce fit model is better because it causes a change in the enzyme active sit and allows the substrate to fit in
Scientific theories can be disproved. This is a key part of the scientific method, creating hypothesis that can be disproved if they are incorrect. However, you can never really prove a hypothesis - you can find evidence that either fits or doesn't fit. If it doesn't fit the hypothesis needs to be revised or thrown out. If the evidence supports the hypothesis, there may be something that you are missing which may reject the hypothesis.