What is a safe dose of Vitamin B12?

Answer 1

B12 is the only vitamin with no known toxic dose, so it should be safe no matter how much you take. Still I wouldn't recommend absurd amounts - if you take 10,000 times the RDA you might be the person to discover the toxic level. At any rate, taking more than recommended doesn't provide additional benefits and is just a waste of money. so what is a recommended dosage?

Answer 2

Research studies have shown that the B vitamins, particularly folate, B12, and B6 help lower homocystein levels, hence the risk of heart attacks. The levels of folic acid and vitamins B6 and B12 needed to achieve this effect, however, are higher than one would get from a typical multivitamin/mineral supplement.1 The standard US RDA just doesnt cut it when it comes to these vitamins; as much as five times the amount of daily recommended B6 is required, whereas as much as thirty to forty times the amount of estimated daily B12 is ideal. Finding a multivitamin that contains the correct dosages is important. In a nutshell, Vitamins B6 and B12 are extremely helpful at protecting the heart and nerves and lowering levels of the damaging homocysteine. For further information on why this works, and a comparison of the products available as supplements, take a look below. A good multivitamin is the foundation of health and nutrition. Take a look at our scientific reviews of many of the popular brands for factors such as ingredients, areas of improvement, quality level, and overall value. If you are looking for a high quality liquid multivitamin, we suggest that you take a look at the Multivitamin Product Comparisons Scientific Explanation:

When it comes to Heart disease, several mechanisms are likely to be involved in the induction of vascular damage by homocysteine. These include endothelial cell desquamation, oxidation of low-density lipoprotein, increased monocyte adhesion to the vessel wall, and impaired vascular response to the endothelium-dependent relaxing factor nitric oxide. An acute increase in plasma homocysteine level has been linked to activation of coagulation. It also impairs hemodynamic and rheologic responses to L-arginine, the natural precursor of nitric oxide, a compound that is responsible for keeping blood vessels open, and whose function homocysteine seems to interfere with.

Reference:

1.Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention. G. Schnyder, M. Roffi, Y. Flammer, et al., The Swiss Heart Study: A randomized controlled trial. JAMA., 2002, vol. 288, pp. 973--979

Answer 3

A safe dose for pyridoxine (vitamin B6) is ten milligrams or less per day. The US RDA for pyridoxine is 2 milligrams.

The upper limits quoted vary considerably worldwide according to the exact regulatory agency. The US FDA set the tolerable upper limit at 100 mg/day in 2000. The European Community Scientific Committee on Food established a tolerable upper intake level of 25 mg/day for adults in 2000. The UK EVM derived a safe upper level of 10 mg/day for a 60 kg adult in 2003.

Excessive levels maintained over a long time can cause skin problems and permanent nerve damage.

Answer 4

yes. it may cause problems in neurological functions.

Answer 5

The recommended dietary allowance (RDA) for vitamin B6 is 2.0 mg/day for the adult man and 1.6 mg/day for the adult woman.

Answer 6

100 mcg