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What is disseminated intravascular coagulation?

Updated: 4/27/2022
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8y ago

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Disseminated intravascular coagulation (DIC) is a pathological process in the body where the blood starts to coagulate throughout the whole body. This depletes the body of its platelets and coagulation factors, and there is a paradoxically increased risk of haemorrhage. It occurs in critically ill patients, especially those with Gram-negative sepsis (particularly meningococcal sepsis) and acute promyelocytic leukemia.

Basically the person is clotting and bleeding at the same time. It is a very very serious disorder, and can be very deadly. Once all of the body's clotting factors are used up (and they can be used up very quickly) then the body just bleeds out of every opening in the body (eyes, nose, ears, mouth, anus, etc.) It can be treated by giving the person blood products to help replenish the volumes being lost and also giving products that will help clot the blood. However sometimes it is too late. The only way to really correct this disorder is to correct whatever the underlying cause for the DIC was.

Disseminated intravascular coagulation is a disorder. When someone has DIC their proteins that control blood clotting becomes over active.

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Disseminated intravascular coagulation (DIC), also known as consumptive coagulopathy, is a pathological activation of coagulation (blood clotting) mechanisms that happens in response to a variety of diseases. DIC leads to the formation of small blood clots inside the blood vessels throughout the body.[1] As the small clots consume coagulation proteins and platelets, normal coagulation is disrupted and abnormal bleeding occurs from the skin (e.g. from sites where blood samples were taken), the digestive tract, the respiratory tract and surgical wounds. The small clots also disrupt normal blood flow to organs (such as the kidneys), which may malfunction as a result.[2]DIC can occur acutely but also on a slower, chronic basis, depending on the underlying problem.[3] It is common in the critically ill, and may participate in the development of multiple organ failure, which may lead to death.[Source:http://en.wikipedia.org/wiki/Disseminated_intravascular_coagulation


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