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Immunosuppressive drugs, immunosuppressive agents, or immunosuppressants are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:

  • Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver)
  • Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, Crohn's disease, pemphigus, and ulcerative colitis).
  • Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic Asthma control).

These drugs are not without side-effects and risks. Because the majority of them act non-selectively, the immune system is less able to resist infections and the spread of malignant cells. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, liver, and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.[1]

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11y ago
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13y ago

Immunosuppressant drugs greatly decrease the risks of rejection, protecting the new organ and preserving its function. These drugs act by blocking the immune system so that it is less likely to react against the transplanted organ.

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11y ago

used to prevent the body from rejecting a transplanted organ.immunosuppressant drugs are also used to treat such severe skin disorders as psoriasis and such other diseases as rheumatoid arthritis,Crohn's disease.and patchy hair loss (alopecia areata)

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13y ago

Some immunosuppressants are also used to treat a variety of autoimmune diseases:.Azathioprine (Imuran).Cyclosporin (Sandimmune, Neoral).Glatiramer acetate (Copaxone).Mycopehnolate (CellCept).Sirolimus (Rapamune)

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13y ago

The four main categories of immunosuppressant drugs currently used in treating patients.Cyclosporins (Neoral, Sandimmune, SangCya). Azathioprines (Imuran). Monoclonal antibodies.Such corticosteroids as prednisolone (Deltasone, Orasone)

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13y ago

Immunosuppressant drugs, also called anti-rejection drugs, are used to prevent the body from rejecting a transplanted organ.

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13y ago

Immunosuppressive-- Any agent that suppresses the immune response of an individual.

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10y ago

A drug that lowers the body's normal immune response.

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14y ago

Most of the people who use immunosuppressive drugs have transplanted organs, so their bodies won't reject the new organ.

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Q: What is immunosuppressive drug?
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Related questions

What kind of drug suppresses the body's immune response?

Immunosuppressive


How many mg of ondansetron do you need to get high?

Ondansetron will not give you a high. It is not that kind of medication, in the same way that you cannot get a high from an blood pressure drug or an immunosuppressive drug.


What are the drug interactions associated with taking the Thunder God vine?

People taking immunosuppressive drugs such as prednisone should not use thunder god vine.


What can be done to reduce the risk of organ rejection?

To prevent the patient from rejecting the donated organ, usually the drug Tacrolimus will be used to immunosuppress the patient. (Although sometimes it's Sirolimus). Steroids are also commonly used alongside the main immunosuppressant.


Is Trichoderma used as a drug in Organ Transplant?

I don't believe so - you are correct in thinking that the first immunosuppressive (Ciclosporin) was derived from a fungus, however that fungus was "Tolypocaldium Inflatum", which as far as I am aware is not related to Trichoderma.Tacrolimus (a more recently developed immunosuppressive) is derived from the bacteria Streptomyces tsukubaensis. Other immunosuppressives ending is "imus" also come from the Streptomyces family.


Immunosuppressive drugs are given after?

organ transplantation


Why are infections a constant risk to a patient on immunosuppressive agents?

Infections are a constant risk while on immunosuppressive agents, because the immune system is supposed to prevent them.


What is a major complication of immunosuppressive therapy?

Increased risk for infection


Were immunosuppression developed in 1954?

No, the first immunosuppressive (ciclosporin) was developed in 1970's.


Does Kidney transplantation require medication?

A regimen of immunosuppressive, or anti-rejection medication, is required after transplantation surgery


What medications are used in the treatment of systemic lupus erythematosus?

There are 4 Food and Drug Administration medications for the treatment of lupus:AspirinPrednisoneHydroxychloroquine (Plaquenil)Belimumab (Benlysta)Off label medications include prescription anti-inflammatories, rituxan (Rituxamab), cytoxan, azathioprine, methotrexate and other immunosuppressive medications.


What has the author David Timothy Shakespeare written?

David Timothy Shakespeare has written: 'Studies on the immunosuppressive action of rat seminal plasma'