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Introduction of p-nitro acetanilide

Updated: 8/11/2023
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9y ago

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The reaction type is EAS (Electrophilic Aromatic Substitution). When dealing with aromatic substitutions you have to take into consideration what positions the different types of substitutes prefer.

In this situation you are dealing with Nitro-groups (NO2), which are said to prefer meta.

The mechanic itself is quite simple, you have to start out by figuring out the product of the reaction between the acids, which generate the nitro-group.

What happens when you add H2SO4 and HNO3 together? (These are the most commonly used reagents in this reaction). You know that one nitro group is generated, the rest is simple. Just remember the ion from sulfur acid, this will play a key role later on.

So NO2 groups are meta-positioning, thus the double bond from the aromat will attack NO2+. After that you draw the resonance, and finish with a hydrogen being attacked by the ion from sulfuric acid, returning the double bond and giving you your product.

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13y ago
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12y ago

when acetone is treated with hno3 in the presence of conc h2so4 get paranitro aacetanalide

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9y ago

property of peranitroacetelide

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Q: Introduction of p-nitro acetanilide
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Why can't acetanilide dissolve in HCl?

Why is not acetanilide soluble in HCL?


Most suitable for recrystallizing acetanilide?

the most suitable for recrystrallizing acetanilide is water..


Will acetanilide dissolve in hot heptane?

Yes. Heptane is an ideal recrystallization solvent for acetanilide.


How can you prepare para-nitro acetanilide from acetanilide?

used of para nitro acet anilide


Is acetanilide an amide?

yes


What is the reaction of acetanilide with litmus?

Acetanilide is a substituted aromatic amide insoluble in water and is almost neutral so does not react with litmus.


Why add nitric acid and sulphuric acid to acetanilide?

HNO3 + H2SO4 acts as a sulphonating agent. It reacts with acetanilide to from 4-Acetylamino-benzenesulfonic acid.


Why is water a good solvent for the crystallization for acetanilide?

It is most useful when crystals are being filtered out of a desired product. Why is water a good solvent for the recrystallization of acetanilide? Acetanilide readily dissolves in hot water, but is insoluble at low temps. Thus, it dissolves in hot water but crystalizes easily when cool.


What is a reason for low yield in the bromination of acetanilide?

Terrible technique


What is the side effects of acetanilide?

acetanilide results in the deactivation of the heamoglobin in some red blood cells. This means they can uptake fewer oxygen molecules therefore you may feel breathless, tired ect


What is melting point of para bromo acetanilide?

166-170 ºC


What are the different substances to which acetanilide form eutectic mixtures?

I don’t know