What is remedy in homeopathy for atypical depression associated with social phobia fatigue both mental and physical?

Answer:
Although homeopathic remedies are prescribed on a constitutional, rather than symptomatic, basis (with the exception of first aid remedies such as Arnica, etc.,) Conium Maculatum is one of the remedies to closely fit the picture that you describe. When it fits, it is an excellent and deep acting remedy. (As a note of interest: Conium Maculatum - not in homeopathic dilution of course - is an old remedy rendered classical by Plato's well-known description of its employment in the death of Socrates.)
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