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What is synaptic facilitation?

Updated: 8/10/2023
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11y ago

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an action will happen cause of axo-axonal syanapse,which can facilitate the nerve impulse transmitting from presynaptic membrane to post synaptic membrane.

In the axo-axonal synapse one axon is secreting serotonin which can influence to close some of K+ channels in the other neuron to maintain a prolonged action potential by slowing down the repolarization.

as long as action potential is there it can stimulate the presynaptic membrane to release neurotransmitters towards postsyanptic membrane so prolonged action potential will help to stimulate more the Post synaptic membrane and give a strong impulse this is called presynaptic facilitation

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11y ago
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11y ago

Presynaptic excitation is also known as the spike broadening affect. It usually occurs between axoaxonic synapses. The first axon depolarizes the second axon, resulting in an increase of sodium and a decrease in potassium. Potassium release is inhibited, causing more neurotransmitter to be released, causing the action potential spike to broaden and the will return to resting potential slower than normal.

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This is a form of homosynaptic plasticity during which a post-synaptic terminal acquire a short efficacy (represented by increase in excitatory post-synaptic potentials (EPSP)) in its strength due to increase in transmitter release from the presynaptic neuron. Usually, when a neuron fires an action potential, voltage gated calcium channels open, allowing calcium to drive the exocytotic machinery to bring about transmitter release. Now this calcium is removed from the presynaptic terminal. However, in synaptic facilitation, the presynaptic neuron fires many action potentials separated by few msecs, this causes the post-synaptic neuron to temporally summate the EPSP, so that the first EPSP is not as big as the second EPSP. This is because, after the first action potential the calcium that accumulated in the presynaptic terminal was not removed completely before the second action potential, this will now make the second action potential to be able to produce larger transmitter release because the concentration of calcium that will enter the presynaptic terminal and the residual calcium from the first action potential will be larger, and therefore will produce more neurotransmitter release.

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Q: What is synaptic facilitation?
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What is the past form of facilitation?

"Facilitation" is a noun, not a verb. Therefore it does not have a "past form".


What is presynaptic inhibition?

Inhibition of a stimulatory neuron before it synapses, by inhibiting Ca2+ entry and blocking downstream processes, preventing neurotransmitter release, and therefore preventing the neuron generating and EPSP post-synaptically.


What is synaptic potential?

synaptic potential


The are sack-like structures found inside the synaptic knob containing chemicals?

synaptic vesicles


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The theory of social facilitation has been used many times by a number of researchers. The biggest known experiment of social facilitation occurred with Yerkes Dowdson's experiment.


What is the small space separating pre and post-synaptic neurons?

synaptic cleft (also known as "synaptic gap")


What causes calcium ions to enter the synaptic bulb?

The nerve signal arrives at a synaptic knob and causes calcium channels to open. This allows the calcium ions to enter the synaptic knob. Calcium ions entry into the synaptic knob triggers exocytosis of synaptic vesicles, which release acetylcholine into the synaptic cleft.


Is synaptic transmission always from pre to post synaptic?

Yes


What are synaptic gaps?

Synaptic gaps are the spaces between neurons.


What is proactive facilitation?

Proactive Facilitation is an increased ability to learn new information based on the presence of previously held information.


What are the tiny sacs found within the terminal button which release chemicals into the synapse?

The tiny sacs in the synaptic knob are known as synaptic vessels. The synaptic vessels release chemicals into the bloodstream with each synapse.


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Facilitation