Depends what you mean by biggest. If you mean most important, then I would think the wheel. If you mean big as in size, then probably something stupid and not even worth mentioning. first the wheel then writting then the microchip.
There are two: whether there is a need for their invention, and is their invention original.
la riata grande. it was one of the biggest invetion
the steam engine
The Quantum Theory.
George Washington Carver's greatest invention is peanut butter.
automobile
The Apple computer.
biggest deer ever?
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NO
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doyou mean who is the biggest slag ever? answer: MOLLY DAVIES:)