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Although HIV-1 and HIV-2 are closely related, they are thought to have jumped from primates to humans at different times (and from different species).

HIV-1 is by far the more virulent of the two species of HIV.

Because HIV-1 is more easily transmitted, it also spreads more readily and therefore accounts for the vast majority of global HIV infections.

HIV-2, because it is much less transmittable, is largely confined to West Africa (where it is thought to have originated) and to West African migrant communities in Europe.

HIV-1 also mutates more efficiently that HIV-2 and generally progesses to AIDS at a significantly faster rate than HIV-2 does.

Also, HIV-2 has Vpr and Vpx proteins. HIV-1 has only Vpr. Differences between these proteins are actually on research.

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Linnea Beatty

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2y ago
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11y ago
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Although HIV-1 and HIV-2 are closely related, they are thought to have jumped from primates to humans at different times (and from different species).

HIV-1 is by far the more virulent of the two species of HIV.

Because HIV-1 is more easily transmitted, it also spreads more readily and therefore accounts for the vast majority of global HIV infections.

HIV-2, because it is much less transmittable, is largely confined to West Africa (where it is thought to have originated) and to West African migrant communities in Europe.

HIV-1 also mutates more efficiently that HIV-2 and generally progesses to AIDS at a significantly faster rate than HIV-2 does.

Also, HIV-2 has Vpr and Vpx proteins. HIV-1 has only Vpr. Differences between these proteins are actually on research.

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10y ago

== == == == HSV-1 is the type whihc usually causes oral herpes and HSV-2 is the type which usually causes genital herpes, however, you can get either type in any location.
Type 1 and Type 2 are caused by two different subtypes of the herpes virus. Type 2 is more likely to recur, and the average is six outbreaks in the first year of infection with Type 2. In contrast, many people with Type 1 cold sores or genital herpes don't get more than one outbreak. There are more people with evidence of prior infection with Type 1 than Type 2.
There is little difference in the two viruses.
There is virtually no difference. Type 1 is referred to as oral herpes; Type 2 as genital herpes.

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Wiki User

11y ago

Not much difference. They are both strains of the HIV virus and both can lead to AIDS and other opportunistic diseases. HIV-2 strain is found mostly in West Africa, with hardly any found in the US and other Western countries.

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14y ago

the two types are herpes type one and type two..ie,HSV1 and HSV2...the difference is in the site of preference

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Wiki User

10y ago

There is not "stage 1" and "stage 2" herpes. There are two types of herpes -- type 1 and type 2. Type 2 is more likely to recur.

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Q: What is the difference between HIV-1 and HIV-2?
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What is more dangerous hiv1 or hiv2?

Both HIV-1 and HIV-2 are equally "dangerous" in that both are sexually transmitted and both lead to AIDS. There are several difference between the two, in terms of how transmissible they are and how each progressess. The bottom line--you want to avoid either type of the virus.


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