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Robitussin with codeine contains guaifenesin, which is an ingredient that is used to treat chest congestion by increasing chest secretions and making it easier for the patient to cough up the secretions.

Promethazine is a drug that is used to treat nausea and vomiting.

Codeine is used in both preparations to treat cough

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14y ago
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13y ago

Well , Nothing Really . . . Promethazine Is Just Muchh Better It Has A Better Effect An Stronger , You Have To take A Lil Bit More Nyquil To Have A Promethazine High If Thas Whut Chu Really Wantt . . An Plus Promethazine Has More Chemicals In It; So More Chemicals Means A Better High !

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9y ago

Promethazine with codeine is a sedative drug used to treat cough and cold symptoms. Codeine Guaifenesin is a cough-suppressing expectorant drug that increases and thins mucus.

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Q: What is the difference between robitussin with codeine and promethazine with codeine?
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