Answer:
Both Inquisitions were similar in the fact that they were both trying to banish heresy from the Catholic church. But there were also a few differences:
The Spanish Inquisition, 1492:
1. Held in Spain.
2. Was to banish Muslims and Jews from Spain.
3. Worked effectively. So effectively, that when Protestantism started, it could not start in Spain.
The Roman Inquisition, 1588-1834:
1. Held all over Europe.
2. Was to quench the Protestant view from the Catholic church.
3. Didn't work very well, the Protestant view kept on preaching, publishing pamphlets, and winning converts.