Answer
Ecstasy, known also as methylenedioxymethamphetamine, is a potent stimulant of the brain. It acts at the synapse by binding preferentially to a protein called SERT (serotonin transporter), a major protein involved in serotonin reuptake at the synapse. With SERT bound by ecstasy, SERT cannot efficiently bind serotonin left in the synapse; thus there is more serotonin left at the synaptic cleft to bind the postsynaptic serotonin receptors. Serotonin pathways are major regulators of mood and the resulting increase in serotonin signaling as seen in ecstasy are thought to contribute heavily to the drug's effects. Similar mechanisms of use are used in drugs such as antidepressants called selective serotonin reuptake inhibitors (SSRIs), although the effects are much less dramatic than those of ecstasy.
First answer by Diberri. Last edit by Diberri. Contributor trust: 120 [recommend contributor]. Question popularity: 24 [recommend question]
|
Research your answer: |



