it can be very deadly. Some people have a allergic reaction like I did with this particular combination. I took about 2 bars and when I was about done with an 8ball (3.5grams) it became really hard to talk. Then within five minutes I could not talk or make any sound at all. I had to write on a piece of paper to my girlfriend that she should take me to the ER. It was really scary. It can also mess your heart up. These drugs are the exact opposites, one is an upper and the other a downer, so it confuses your. It is very dangerous, please do not try this!