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It serves as 'The DNA Unwinding Enzyme'. It must needs be that other histone related protein-enzymes are needed for "rewinding".

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Francesca Feil

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2y ago
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9y ago

DNA helicase "unzip," or separate, a strand of DNA at positions called origins. This means that the hydrogen bonds between complementary base pairs are removed (DNA is double stranded!). When they separate double-stranded DNA into single strands, it allows each strand to be copied (replication).

The helicases create "forks", which grow bidirectional from the origin. A number of proteins are associated with the replication fork, which helps in terms of the initiation and continuation of DNA synthesis. One protein, the DNA polymerase, creates the new DNA by adding complementary nucleotides to the template strand.

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12y ago

For simplicities sake, DNA can be thought of as a zipper. Think of two separate pieces that are held together by hydrogen bonds. The job of Helicase is to unzip the DNA strand by breaking the hydrogen bonds that hold them together, and it does this by moving along the strand of DNA, very much like on an actual zipper.

Because of this type of movement, helicase is a type of `motor protein.`

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12y ago

It serves as 'The DNA Unwinding Enzyme'. It must needs be that other histone related protein-enzymes are needed for "rewinding".

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12y ago

Helicase will unwind the double stranded helical structure of DNA so that DNA polymerase can attach and synthesize a new DNA strand. This is the process of DNA repicaltion

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Anonymous

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3y ago

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Q: What is the main function of DNA helicase in DNA replication?
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