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The mechanisms involve simple aromatic electrophilic substitutions. In making this compound, we simply nitrate benzene, then reduce it down with a reducing agent such as LiAlH4 in ether then water. Next, we must protect the highly reactive amino group with acetyl chloride. Then, simply brominate with an FeBr3 catalyst...and you have the compound in high yield. Acidification would also give a nice yield of p-bromoaniline. Dr Jim Romano CEO Orgoman.com and Romano Scientific, New York

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13y ago
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9y ago

To make a preparation of p-bromoacetanilide, put the solution in a flask with a round bottom. Reflux it in water bath with HCl and ethanol for thirty minutes. Then cool in an ice bath.

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12y ago

no reaction

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Q: The reaction mechanism involved in the preparation p-bromoacetanilide?
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