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Protein Synthesis

Endoplasmic Reticulum-->cis Golgi cisternae --> medial Golgi cisternae --> trans Golgi Cisternae --> Plasma membrane

Extra Cellular Space

As they are being synthesized, secretory proteins enter the lumen of the endoplasmic reticulum. From the ER, vesicles transport these proteins to the Golgi, where they are sequentially modified and concentrated in a cis-to-trans direction. Secretory vesicles bud from the Golgi and move along cytoskeletal filaments to eventually fuse with the plasma membrane, secreting their protein cargo. Each of these transport steps requires specialized proteins to ensure that the cargo is sent to the proper location and is able to fuse with the target membrane.

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13y ago
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9y ago

These proteins travel through cells in the following pattern:

Protein Synthesis ---> Endoplasmic Reticulum ---> cis Golgi cisternae ---> medial Golgi cisternae ---> trans Golgi cisternae ---> Plasma Membrane

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13y ago

Ribosome on RER--->vesicle--->cis Golgi-->trans Golgi-->vesicle-->plasma membrane-->exocytosis.

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12y ago

Endoplasmic Reticulum-->Golgi apparatus-->vesicles that fuse with plasma membrane

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9y ago

The most likely pathway is ER (endoplasmic reticulum) -> Golgi -> vesicles that fuse with plasma membrane.

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12y ago

Rough ER, Golgi apparatus, Secretory vesticles, Plasma membrane

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Q: What are the steps of the secretory pathway?
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