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What is the prognosis for megalencephaly?

Updated: 8/30/2023
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GaleEncyofNeuroDis

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13y ago

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The prognosis for babies with periventricular leukomalacia is dependent on the other complications of prematurity that a baby may face. Deficits may range from mild to devastating disability or even death.

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13y ago
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13y ago

The prognosis for megalencephaly varies according to the presence and severity of associated problems such as intractable seizures, paralysis, and mental retardation

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Q: What is the prognosis for megalencephaly?
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Related questions

How common is Megalencephaly?

The incidence of megalencephaly is estimated at between 2% and 6%. There is a preponderance of affected males; megalencephaly affects males three to four times more often than it does females


What are the causes of Megalencephaly?

Most often, megalencephaly is a familial trait that occurs without extraneural (outside the brain) findings. Familial megalencephaly may occur as an auto-somal dominant (more common) or autosomal recessive condition


What non-genetic factors can contribute to the development of megalencephaly?

Non-genetic factors such as a transient disorder of cerebral spinal fluid may also contribute to the development of megalencephaly


What are the neurological manifestations of Megalencephaly?

Manifestations may range from normal intellect, as with case of benign familial megalencephaly, to severe mental retardation and seizures, as with Alexander disease, an inherited leukodystrophy


How is Megalencephaly diagnosed?

The evaluation of a patient with suspected megalencephaly will usually consist of questions about medical history and family history, a physical exam that includes head measurements, and a developmental and/or neurological exam


What kind of disorder is megalencephaly?

According to the National Institute of Neurological Disorders and Stroke (NINDS), megalencephaly is one of the cephalic disorders, congenital conditions due to damage to or abnormal development of the nervous syst


What is megalencephaly?

Megalencephaly (also called macrencephaly) describes an enlarged brain whose weight exceeds the mean (the average weight for that age and sex) by at least 2.5 standard deviations (a statistical measure of variation).


What type of interventions may be useful for patients with Megalencephaly?

Interventions such as speech, physical, and occupational therapy may be indicated for individuals with megalencephaly. Early intervention services for young children and special education or other means of educational support for school-aged children


What is the treatment for Megalencephaly?

Management of this condition largely depends upon the presence and severity of associated neurological and physical problems


What is the prediction of a disease's outcome?

Prognosis Pro = prior or before Gnosis = knowledge


What is the prognosis for abulia?

The prognosis of abulia depends on the prognosis of the underlying condition.


What is the prognosis?

a prognosis is the result after treating the disease