Pallidotomy is major surgery on the brain. It may cause excessive bleeding, and care must be taken in patients susceptible to uncontrolled bleeding or who are on anticoagulant therapy.
Unilateral (one-sided) pallidotomy may be used if symptoms are markedly worse on one side or the other, or if the risks from bilateral (two-sided) pallidotomy are judged to be too great.
The surgical candidate should discuss all the surgical options with the neurologist before deciding on pallidotomy. A full understanding of the risks and potential benefits must be understood before consenting to the surgery.
While there are several controversies in the field of PD surgery, all experts agree that risks are reduced in procedures performed by the most experienced neurosurgeons.
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Pallidotomy is performed in the hospital by a neurosurgeon, in coordination with the patient's neurologist.
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For unilateral pallidotomy, a single "burr hole" is made in the top of the skull; bilateral pallidotomy requires two holes.
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Pallidotomy mimics this action by permanently destroying the GPi cells.
The key to successful outcome in pallidotomy is extremely precise placement of the electrode.