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This is a blood test to detect the presence of HLA-B27 in white blood cells.

The test is conducted to look for specific protein found on the surface of white blood cells. The protein is called human leukocyte antigen B27 (HLA-B27) that help the body's immune system tell the difference between its own cells and foreign, harmful substances.

The test is referred when you have symptoms of chronic inflammation, pain, and stiffness in certain areas of your body, such as your back, neck, and chest, or eyes, especially if you are male. A positive test means HLA-B27 is present. It suggests a greater-than-average risk for developing Ankylosing spondylitis, Reiter syndrome or Sacroiliitis (inflammation of the sacroiliac joint).

If HLA-B27 is not present, then the association is not there.

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13y ago
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10y ago

The HLA B27 is a leukocyte antigen. An HLA B27 test is done to check the protein found on the surface of white blood cells. This antigen helps the body's immune system determine its own cells and harmful substances.

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Q: What does a HLA-B27 blood test detect?
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