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The first stage of syphilis is where a chancre appears at the site of infection.

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Q: Which stage of syphilis is characterized by the presence of a chancre?
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If you even slightly suspect that you have this disease, go to a doctor, clinic, or or public service organization to be checked. Syphilis is curable, especially in the early stages, using antibiotics. But if it is not treated, it can kill you. You will need to have a blood test to know for sure.The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration), secondary syphilis with a diffuse rash which frequently involves the palms of the hands and soles of the feet, latent syphilis with little to no symptoms, and tertiary syphilis with gummas, neurological, or cardiac symptoms. It has, however, been known as "the great imitator" due to its frequent atypical presentations. Diagnosis is usually via blood tests; however, the bacteria can also be detected using dark field microscopy.


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Syphilis is a common sexually transmitted disease caused by the bacteria Treponema pallidum. The main form of transmission occurs through sexual contact, though syphilis can also be transferred from the mother to the fetus during pregnancy and birth. Millions of people throughout the world today have contracted syphilis, with rates increasing dramatically within developing countries.Causes and ProgressionBecause syphilis is a sexually transmitted disease, it can be transferred through contact of broken skin and mucous membranes. Additionally, congenital syphilis occurs when a pregnant mother transmits the bacteria to the developing baby. The progression of syphilis can be documented in three stages. During the primary stage, painless sores develop at the site of initial infection, often disappearing in about five weeks. As the sores form, the bacteria collect within the body in an inactive form. In the secondary stage, untreated syphilis manifests in a variety of forms. Common symptoms include red rashes that spread over the body, and wart-like lesions within mucous membranes. It is important to realize that syphilis is extremely contagious during these first two stages. Finally, the tertiary stage is characterized when the bacterial infection spreads throughout the entire body. The bacteria can migrate to the nervous system, brain, heart, and skin. Extensive damage occurs to the points of bacterial migration; the tertiary stage occurs three years after the initial infection.SymptomsBecause syphilis progresses over many years, specific symptoms depend on the stage of syphilis. Common symptoms include painless sores, swollen lymph nodes, fever, rashes, and aches. Tertiary stage symptoms include problems to the heart, brain, and nervous system.TreatmentSyphilis can be effectively treated and cured if detected during the initial, early stages of infection. Antibiotics such as penicillin remain as the most effective treatment plan to combat syphilis. After initial treatment, blood tests must be conducted for the next two years to ensure the complete eradication of the syphilis bacteria. However, syphilis is very hard to treat when it reaches the tertiary stage. Further antibiotic treatment plans will limit further syphilis progression, but cannot undo the damage the bacteria have already done. Hence, late-stage syphilis may result in long-term health problems in numerous body systems. Constant therapy will be required to treat the body's long-term issues.