In 1972, Hal Holbrook and Martin Sheen stared as a gay couple in an ABC made-for-TV movie called "That Certain Summer." In 1975, an ABC series called "Hot l Baltimore" featured a gay couple called George and Gordon.
In 2003, CBS' show "Amazing Race 4" featured a real-life married same-sex couple named Reichen and Chip.
Happy days
the Munsters.
Fred and Velma (or Welma) Flintstone.
No. They may have been the first "multiracial" couple on television, if you accept that "of Spanish descent" is a different "race" than "white".
Mary Kay and Johnny were the first couple to appear in bed together in a prime time television show, it was actually the fist sitcom on television in 1947. http://www.snopes.com/radiotv/tv/marykay.asp
St Elsewhere
Eureka is partially good but lacks the depth after the first couple episodes. Even so it can humor you for a couple of seasons but nothing great about it.
Mike and Carol Brady
I believe it was the show in 50s "I love Lucy". She was white and he was Cuban.
First of all "the" is not a letter is is a word! The avengers The simpsons The odd couple
My bet would be Ozzie & Harriet Nelson. They had a very popular tv situation comedy show.
She is a legend, I Love Lucy was the first comedy show ever and Lucille ball and Desi Arnez were the first comedy couple on tv