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skin cancer doesn't arise from the stratum corneum because that layer of the epidermis is composed mainly of dead cells that do not have a blood supply for cancer cells to use.

Foremost the Stratum Corneum is the top layer of the Epidermis, a cutaneous membrane. It is to be noted that the Stratum Corneum consists of 25-30 layers of non-dividing or dead cells. Therefore this environment does not accomodate the malignant cancer cells that depend on a living healthy area in which to chronically divide.

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Q: Why doesn't skin cancer arise from the stratum corneum?
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