Platelets are made in bone marrow, the tissue located inside of bones. Abnormally high platelet production may occur independently, for reasons that are not known (primary th…rombocythemia ), or as a symptom of another condition ( secondary thrombocytosis ). Causes of high platelets in primary thrombocythemia- In this condition, the bone marrow makes too many platelets. This condition may be inherited. Causes of high platelets in secondary thrombocytosis- Thrombocytosis is the occurrence of high platelets as a symptom of another condition. A wide range of diseases and conditions may cause high platelets including: .
Anemia (low red blood cell count) .
Blood loss .
Chronic myelogenous leukemia (type of cancer that develops in the bone marrow, the soft tissue inside bones that helps form blood cells) .
Inflammatory disorders such as Kawasaki disease (rare childhood disease that involves inflammation of the blood vessels) .
Myelodysplasia (group of conditions in which the blood cells are abnormal in development or function) .
Myelofibrosis (disorder that results in scar tissue in the bone marrow) .
Polycythemia vera (rare bone marrow disorder causing excessive production of blood cells) .
Reaction to certain medications, including steroids .
Splenectomy (surgical removal of the spleen) (MORE)