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When a female horse and a male donkey mate, you get a mule, but two mules can’t mate to create another mule because of their chromosomal makeup.

A mule gets 32 horse chromosomes from its mother and 31 donkey chromosomes from its father. Mules are almost always sterile because those chromosomes don’t match up well enough to create egg or sperm cells.

I say “almost always” because there have been a few extremely rare instances of female mules reproducing with a male donkey or horse. But those are so rare they’re often called “miracles,” and there have been no documented instances of a male mule fathering any offspring. So, as far as we know, two mules cannot reproduce.

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Willy Quitzon

Lvl 10
4y ago
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Gerardo Glover

Lvl 13
1y ago

Mules are unable to reproduce. This is because they have the wrong number of chromosomes to make either a horse or a donkey. Thus, they cannot have children.

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Wiki User

13y ago

The correct answer is beceayse a mule does not have a even number of chromosomes. They have 63 chromosomes.

A mule is the product of two different species (a horse and a donkey) mating with each other. Mules are always sterile because horses and donkeys have different chromosome numbers.

For the mule, having parents with different chromosome numbers isn't a problem. During mitotic cell division, each of the chromosomes copies itself and then distributes these two copies to the two daughter cells. In contrast, when the mule is producing sperm or egg cells during meiosis, each pair of chromosomes (one from Mom and one from Dad) need to pair up with each other. Since the mule doesn't have an even number of homologous pairs (his parents had different chromosome numbers), meiosis is disrupted and viable sperm and eggs are not formed.

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Wiki User

12y ago

Horses and donkeys have a different number of chromosomes. when they breed, their offspring (a mule) will, to put it simply, have all it's chromosomes somewhere in between the number of donkey chromosomes and horse chromosomes and will not develop the ability to breed. Actually though, some female mules have had foals. Male mules are always sterile.

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Wiki User

9y ago

Mules are unable to reproduce. This is because they have the wrong number of chromosomes to make either a horse or a donkey. Thus, they cannot have children.

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Wiki User

15y ago

This animal is F2 sterile secondary to a mutation on the 12th chromosome.

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Wiki User

11y ago

Because Horses and Donkeys being different species have an uneven amount of chromosomes, only female mules can reproduce on a rare occasion.

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