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Yes.

Bactrim is a type of antibiotic medication.

Excedrin is an over-the-counter medication used to treat pain, which contains three ingredients: acetaminophen (Tylenol), aspirin (non-steroidal-anti-inflammatory), and caffeine.

None of these should interact with each other.

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Q: Can i take sulfamethoxazole and Excedrin together?
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